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A patient with PSP demonstrates bilateral hypometric saccades, bilateral low-gain pursuit, vertical gaze palsy, and normal vestibulo- ocular reflexes. A second PSP patient is unable to make saccades or pursue horizontally. With optokinetic stimulation, the eyes move somewhat. Cold caloric stimulation causes tonic ipsilateral deviation with absent contralateral fast phases. Finally, the eye movement abnormalities in patients with basal ganglionic disease are summarized.
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Robert B. Daroff, MD, Professor of Neurology, School of Medicine, CASE Western Reserve University, University Hospitals - Case Medical Center
Spencer S. Eccles Health Sciences Library, University of Utah