Translation normally occurs in a linear fashion reading nonoverlapping nucleotide triplets. Alternatively, some genes require translation in two overlapping reading frames. The ability of the ribosome to change to an alternative reading frame is called frameshifting. Frameshifting occurs at a specific site in the mRNA sequence, which usually allows the tRNA(s) bound to the ribosome to repair in the new reading frame. Frameshifting can be stimulated by both cis
Type
text;
citation_publisher
University of Utah
citation_keywords
Cell Physiology;
Subject (MESH)
Polyamines; Signal Transduction;
citation_dissertation_institution
University of Utah;
citation_dissertation_name
PhD;
citation_language
en;
Relation-Is Version Of
Digital reproduction of “Polyamine stimulation of antizyme frameshifting”. Spencer S. Eccles Health Sciences Library.
