A 24-year-old man with a 3-day history of headache and vomiting followed by diplopia, facial weakness and seizures.
VA: 20/20 OU declining to HMat 6" OD, 20/50 OS
GFAP-expressing cells embedded within reactive subdural arachnoid tissue.
Primary diffuse leptomeningeal gliomatosis
Surgery: IV Steroids; Alkylating antineoplastic agents
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2.Dorner, L., et al., Primary diffuse leptomeningeal gliomatosis in a 2-year-old girl. Surg Neurol, 2008.
3. Beauchesne, P., et al., Aggressive treatment with complete remission in primary diffuse leptomeningeal gliomatosis - a case report. J Neurooncol, 37(2): p. 161-7, 1998.