Ataxic Optic Neuropathy

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Identifier walsh_2001_s2_c2
Title Ataxic Optic Neuropathy
Creator Madhav Thambisetty
Subject Gait Ataxia; Papilledema; Paraneoplastic Polyneuropathy; Nerve Tissue Proteins; Lung Neoplasms; Autoantibodies
History A 72-year old female with a 5-month history of progressive, bilateral decline in visual acuity and gait ataxia. Previous history significant for depression, abdominal hysterectomy and bilateral carotid endarerectomy. Smoker.
Pathology Bilateral optic neuropathy
Disease/Diagnosis Small cell carcinoma of the lung
Clinical VA: 20/400 OU; RAPD OS
Presenting Symptom Progressive bilateral decline in visual acuity; Ataxic gait
Neuroimaging CT
Treatment Antineoplastic agents; Plasmapheresis
Date 2001
References 1. Yu Z, Kryzer TJ, Griesmann GE, et al. CRMP-5 neuronal autuantibody: maker of lung care and thymoma related autoimmunity. Ann Neurol 2000. 2. Wang L-H, Strittmatter SM. A family of rat CRMP genes is differentially expressed in the nervous system. J Neuroscience 1996; 16(19):6197-6207. 3. Kamata T, Subleski M, Hara Y, et al. Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance. Mol Brain Res 1998; 54:219-236.
Language eng
Format application/pdf
Type Text
Source 27th Annual North American Neuro-Ophthalmology Society Meeting, Frank B. Walsh Session CD-ROM
Relation is Part of Case 2, Session II, Walsh Session, NANOS 2001
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6ns0xk4
Contributor Primary Thambisetty, Madhav
Contributor Secondary Scherzer, C.A; Yu, Z,; Lennon V.A.; Newman, N.J.
Setname ehsl_novel_fbw
ID 177713
Reference URL https://collections.lib.utah.edu/ark:/87278/s6ns0xk4