| Publication Type |
dissertation |
| School or College |
College of Engineering |
| Department |
Chemical Engineering |
| Author |
Kandadai, Madhuvanthi A |
| Title |
Rheology and interfacial tension of biopolymers |
| Date |
2010 |
| Description |
The rheology and interfacial tension of biomaterials are important factors governing their potential use in biomedical applications. This dissertation presents a study of the rheology and interfacial tension of three very different biomaterials: (1) A hydrophobically modified Hyaluronic acid (HA) with polypeptide side chains, (2) Actin fibers and (3) a highly hydrophobic fluoroalkane, Perfluoropentane, and the effect of various surfactants and their mixtures on lowering its interfacial tension in an aqueous interface. In Chapter 1, we present a description of the properties and applications of these materials and a detailed literature review relevant to our studies to better understand the motivation of our work. In Chapter 2 we describe the techniques used for our studies. In Chapter 3, we present our studies on the hydrophobically modified HA with polyleucine side chains and compare them to unmodified HA of same or similar backbone molecular weights. We found a significantly enhanced viscosity for the modified HA compared to unmodified HA at the same concentration. We also found a viscoelastic behavior that was dependent on the concentration of the solution and grafting ratio of the hydrophobic side chains. The associative thickening properties of modified HA investigated with various rheological experiments and simulation results are presented in this chapter. |
| Type |
Text |
| Publisher |
University of Utah |
| Subject |
Actin protein; Associative thickening; Hyaluronic acid; Interfacial tension; Perfluoropentane |
| Subject LCSH |
Biopolymers; Rheology |
| Dissertation Institution |
University of Utah |
| Dissertation Name |
PhD |
| Language |
eng |
| Rights Management |
©Madhuvanthi A. Kandadai |
| Format Medium |
application/pdf |
| Format Extent |
1,618,437 bytes |
| Source |
Original in Marriott Library Special Collections, QP6.5 2010.K36 |
| ARK |
ark:/87278/s69317n4 |
| Setname |
ir_etd |
| ID |
192338 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s69317n4 |
