μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans
citation_date
2008
Description
Synaptic vesicles must be recycled to sustain neurotransmission, in large part via clathrin-mediated endocytosis. Clathrin is recruited to endocytic sites on the plasma membrane by the AP2 adaptor complex. The medium subunit (u 2) of AP2 binds to cargo proteins and phosphatidylinositol-4,5-bisphosphate on the cell surface.
Gu, M., Schuske, K., Watanabe, S., Liu, Q., Baum, P., Garriga, G., & Jorgensen, E. M. (2008). μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans. Journal of Cell Biology, 183(5), 881-92.
Rights Management
(c) Gu, M., Schuske, K., Watanabe, S., Liu, Q., Baum, P., Garriga, G., & Jorgensen, E. M., 2008. Originally published in J. Cell Biol., 183(5): 881-92. http://creativecommons.org/licenses/by-nc-sa/3.0/