Bastiani, Michael; Bandyopadhyay, Pradip K.; Olivera, Baldomero M.; Golic, Kent G.
citation_other_author
Rong, Yikang S.; Titen, Simon W.; Xie, Heng B.; Golic, Mary M.; Brodsky, Michael; Rubin, Gerald M.
citation_title
Targeted mutagenesis by homologous recombination in D. melanogaster
citation_date
2002
Description
We used a recently developed method to produce mutant alleles of five endogenous Drosophila genes, including the homolog of the p53 tumor suppressor. Transgenic expression of the FLP site-specific recombinase and the I-SceI endonuclease generates extrachromosomal linear DNA molecules in vivo.
Type
text;
citation_publisher
Cold Spring Harbor Lab Press
citation_firstpage
1568
Citation_lastpage
1581
citation_keywords
Mutations; Drosophila; Gene targeting
citation_language
eng;
Bibliographic Citation
Rong, Y. S., Titen, S. W., Xie, H. B., Golic, M. M., Bastiani, M., Bandyopadhyay, P., Olivera, B. M., Brodsky, M., Rubin, G. M., & Golic, K. G. (2002). Targeted mutagenesis by homologous recombination in D. melanogaster. Gene & Development, 16, 1568-81.
Rights Management
(c) Cold Spring Harbor Laboratory Press-CSHL Press
